Head

 

spisanie Detski i infektsiosni

Editor:
Central Medical Library ®,
MU - Sofia

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 


Journal "Detski i infectsiosni bolesti" (Pediatric and Infectious Diseases)

REVIEWS

bar626

 

Vol. 9, 2017

2/2017

CHILD DISEASES

REVIEWS

E. Ivanova and Sn. Mihaylova. Immunological disturbances in patients with autism spectrum disorders - Detski i infectsiosni bolesti, V. 9, 2017, No 2, 3-8. (Abstract)

 

INFECTIOUS DISEASES

REVIEWS

V. Doycheva, Y. Mitova, Ts. Mincheva and J. Donkov. Epidemiological characteristics of viral hepatitis E in Europe disorders - Detski i infectsiosni bolesti, V. 9, 2017, No 2, 19-22. (Abstract)

V. Doycheva, Y. Mitova, J. Donkov and Ts. Mincheva. Modern epidemiological characteristics and distribution of plague in the world  disorders - Detski i infectsiosni bolesti, V. 9, 2017, No 2, 23-27. (Abstract)

__________________________________________________________________________________

 

1/2017

CHILD DISEASES

REVIEWS

E. Ivanova and P. Manolova-Koleva. Some рeculiarities of speech disorders and minimal physical abnormalities with craniofacial localization in patients with schizophrenia - Detski i infectsiosni bolesti, V. 9, 2017, No1, 3-8. (Abstract)

INFECTIOUS DISEASES

REVIEWS

V. Doycheva, Y. Mitova-Mineva, S. Angelova and J. Donkov. Distribution and epidemiological characteristics of HIV infection and AIDS in Europe in 2015- Detski i infectsiosni bolesti, V. 9, 2017, No1, 13-17. (Abstract)

P. Ganeva, R. Komitova and J. Seimenska. Congenital zika syndrome18 - Detski i infectsiosni bolesti, V. 9, 2017, No1, 18-23. (Abstract)

V. Doycheva, Y. Mitova, S. Angelova and N. Chumak. Modern distribution and epidemiological characteristics of cholera in the world - Detski i infectsiosni bolesti, V. 9, 2017, No1, 24-28. (Abstract)

 

bar626

 

2/2017

CHILD DISEASES

REVIEWS

Immunological disturbances in patients with autism spectrum disorders - Detski i infectsiosni bolesti, V. 9, 2017, No 2, 3-8.
E. Ivanova1 and Sn. Mihaylova2
1Clinic of Psychiatry, UMHAT “Alexandrovska” – Sofia
2Clinic of Clinical immunology with Stem Cell Bank, UMHAT “Alexandrovska” – Sofia
Abstract. Data from the medical literature on immunological examinations conducted in patients with autism spectrum disorders reveals the presence of disorders in cellular and humoral immunity, immunoglobulins, serum levels and genetic polymorphisms of some of the cytokines, presence of autoantibodies, etc., possibly related to the predisposition for the development of this disease, its course and the severity of its clinical symptoms. Research efforts are focused on the development of immunological biomarkers to be used for diagnostic, therapeutic and prognostic purposes in patients with autism spectrum disorders.
Key words: autism spectrum disorders, immunological disorders
Address for correspondence:  E. Ivanova,  MD, 1 Clinic of Psychiatry, UMHAT “Alexandrovska” – Sofia; GSM: 0895472527   е-mail: helen_aivan@abv.bg

 

INFECTIOUS DISEASES

REVIEWS

Epidemiological characteristics of viral hepatitis E in Europe disorders - Detski i infectsiosni bolesti, V. 9, 2017, No 2, 19-22.
V. Doycheva, Y. Mitova, Ts. Mincheva and J. Donkov
Department of Epidemiology, Medical University – Sofia
Abstract. In the last 10 years the number of the patients with HEV has been increasing in European countries and shows variability among different geographical areas. In this review we describe the general epidemiological characteristics of HEV and the serological data in different European countries. Subtypes 3e and f of HEV are the main genotypes detected in the European population. Sporadic cases of autochthonous genotype 4 have been described in Spain, France and Italy. The patients are predominantly male, over 50 years of age. The subclinical form is the most frequent. Fulminant form is rare, predominantly in pregnant women and it was related to genotype 3 of virus.
Key words: viral hepatitis E infection, hepatitis E virus (HEV), genotypes, epidemiological characteristics
Address for correspondence:   Prof. V. Doycheva, MD, PhD, Chair of Epidemiology, MU-Sofia, Zdrave Str No2, 1431 Sofia, e-mail: v.doycheva@abv.bg

 

Modern epidemiological characteristics and distribution of plague in the world  disorders - Detski i infectsiosni bolesti, V. 9, 2017, No 2, 23-27.
V. Doycheva, Y. Mitova, J. Donkov and Ts. Mincheva
Department of Epidemiology, Medical University – Sofia
Abstract. Plague is a bacterial zoonotic infection transmitted by fl eas. The geographical distribution of the disease is strictly localized. The pathogen Yersinia pestis infects humans through infected fl ea bites. Human plague is a serious disease, particularly in its septicaemic and pneumonic forms. The principal animal reservoir and local socioeconomic conditions are determinants of the epidemiological characteristics of the disease and the risk of transmission to human. Plague is a disease of poverty in Africa, South America and Asia (India), where the animal reservoir essentially comprises commensal rodents, but tends to be sporadic disease associated with outdoor occupation in the other endemic regions.
Key words: plague, Yersinia pestis, epidemiological characteristics, geographical distribution
Address for correspondence:
   Prof. V. Doycheva, MD, PhD, Chair of Epidemiology, MU-Sofia, Zdrave Str No2, 1431 Sofia, e-mail: v.doycheva@abv.bg

___________________________________________________________________________

 

1/2017

CHILD DISEASES

REVIEWS

Some рeculiarities of speech disorders and minimal physical abnormalities with craniofacial localization in patients with schizophrenia - Detski i infectsiosni bolesti, V. 9, 2017, No1, 3-8.
E. Ivanova1 and P. Manolova-Koleva2

1Clinic of Psychiatry, University Multiprofile Hospital for Active Treatment “Alexandrovska” – Sofia
2Center for Mental Health – Plovdiv
Summary. Minimal physical anomalies (MРA) have a common embryonic origin with the brain. The discovery of dysmorphologic traits in schizophrenic patients directs to impaired development of ectodermal structures during embryogenesis. MРA with craniofacial localization are deviations in the early development of separate structures in the head, eyes, ears, mouth (gothic palate and tongue) and others. In patients with schizophrenic psychoses and MFA, a greater severity of the clinical picture, a less favorable course, poor prognosis, and possible therapeutic resistance is suggested.
Key words: minimal physical abnormalities, gothic palate, schizophrenia
Address for correspondence: E. Ivanova, MD; GSM: 0895472527; е-mail: helen_aivan@abv.bg

 

INFECTIOUS DISEASES

REVIEWS

Distribution and epidemiological characteristics of HIV infection and AIDS in Europe in 2015- Detski i infectsiosni bolesti, V. 9, 2017, No1, 13-17.
V. Doycheva, Y. Mitova-Mineva, S. Angelova and J. Donkov.
Department of Epidemiology, Medical University – Sofia
Summary. In the review the epidemiological characteristics of HIV-infection and AIDS in Europe in 2015 are discussed. The trends in distribution of infection over the last 10 years in different geographical areas of the WHO European Region and in the countries of EU/EEA are identified. The anti-epidemic and prophylactic measures to counteract future spread of HIV-infection and AIDS in European countries to reach the strategic goal 90-90-90 are summarized.
Key words: HIV-infection, AIDS, epidemiological characteristics
Address for correspondence: Prof. V. Doycheva; e-mail: v.doycheva@abv.bg


Congenital Zika syndrome18 - Detski i infectsiosni bolesti, V. 9, 2017, No1, 18-23.
R. Ganeva1, R. Komitova2 and J. Seimenska3
1Student, Faculty of Medicine, Medical University – Plovdiv
2Department of Infectious Diseases, Parasitology and Tropical Medicine,
Faculty of Medicine, Medical University – Plovdiv
3Student, Faculty of Public Health, Medical University – Plovdiv
Summary. Unlike its mosquito-borne relatives, such as dengue, West Nile, and Japanese encephalitis viruses, which can cause severe human diseases, Zika virus (ZIKV) has emerged from obscurity by its association with a suspected congenital ZIKV syndrome. The massive epidemics in two Pacific islands in 2007 and 2013 were followed by explosive outbreaks in Latin America in 2015. Among brain defects, microcephaly, brain calcifications and ventriculomegaly are the most frequent abnormalities of the central nervous system detected so far. Тhe full clinical spectrum of congenital ZIKV syndrome has yet to be elucidated. It is also paramount to address the larger proportion of ZIKV exposed infants who are asymptomatic at birth but may develop problems later in life. Laboratory diagnosis in endemic countries is a challenge confounded by cross-reactivity with other circulating flaviviruses. Epidemic containment requires improved vector control, as well as development of point-of-care laboratory diagnostics and vaccines suitable for use in pregnant women and neonates. The authors review clinical presentations of congenital ZIKV syndrome, approach to an infected or exposed infant as well as prophylaxis of ZIKV infection.
Key words: zika virus, congenital syndrome, microcephaly
Address for correspondence: Prof. R. Komitova; Plovdiv; GSM: +359 882 495 800


Modern distribution and epidemiological characteristics of cholera in the world - Detski i infectsiosni bolesti, V. 9, 2017, No1, 24-28.
V. Doycheva, Y. Mitova, S. Angelova and N. Chumak

Department of Epidemiology, Medical University – Sofia
Summary. Cholera is an anthroponotic intestinal infection disease. Its significance is determined by the high contagiousness, large geographical dissemination, severe clinical course, high lethality. In this overview the epidemiological characteristics and dissemination of cholera in the different regions of the world in recent years are presented. With increasing of migration from endemic for cholera areas the danger increases and there is a growing risk of imported cases of infection, which requires strict anti-epidemic measures for control and surveillance of cholera.
Key words: cholera, geographical distribution, epidemiological characteristics, prevention and control with epidemic and pandemic distribution
Address for correspondence: Prof. V. Doycheva; e-mail: v.doycheva@abv.bg

 

 

bar626

 

 

Last update: 07.03.2018